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SMILES: OC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)COc1ccccc1\N=N\c1ccccc1OCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O

InChI Key: InChIKey=ISUSJDCLEWDXEU-VNFHBVCDSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50378793   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Membrane-bound transcription factor site-1 protease


(Homo sapiens (Human))		BDBM50378793
PNG
(CHEMBL1170298)
Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)COc1ccccc1\N=N\c1ccccc1OCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O |r|
Show InChI InChI=1S/C52H50N6O10/c59-47(53-41(29-35-17-5-1-6-18-35)49(61)55-43(51(63)64)31-37-21-9-3-10-22-37)33-67-45-27-15-13-25-39(45)57-58-40-26-14-16-28-46(40)68-34-48(60)54-42(30-36-19-7-2-8-20-36)50(62)56-44(52(65)66)32-38-23-11-4-12-24-38/h1-28,41-44H,29-34H2,(H,53,59)(H,54,60)(H,55,61)(H,56,62)(H,63,64)(H,65,66)/b58-57+/t41-,42-,43-,44-/m0/s1
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Article
PubMed
 1.40E+5n/an/an/an/an/an/an/an/a



Indian Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of human recombinant solubule Kexin isozyme 1

Bioorg Med Chem Lett 20: 3977-81 (2010)


Article DOI: 10.1016/j.bmcl.2010.04.101
BindingDB Entry DOI: 10.7270/Q2G44R73
More data for this
Ligand-Target Pair