BDBM50379177 CHEMBL2010834

SMILES: CNC(=O)c1ccc(CC(=O)N(C)C2CCN(Cc3ccc(cc3)C(F)(F)F)CC2)cc1

InChI Key: InChIKey=HREXSEDWNZLPCX-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50379177   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379177 (CHEMBL2010834) Show SMILES CNC(=O)c1ccc(CC(=O)N(C)C2CCN(Cc3ccc(cc3)C(F)(F)F)CC2)cc1 Show InChI InChI=1S/C24H28F3N3O2/c1-28-23(32)19-7-3-17(4-8-19)15-22(31)29(2)21-11-13-30(14-12-21)16-18-5-9-20(10-6-18)24(25,26)27/h3-10,21H,11-16H2,1-2H3,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Astrazeneca U K Ltd Curated by ChEMBL					Assay Description Binding affinity to human ERG				Bioorg Med Chem Lett 21: 7310-6 (2011) Article DOI: 10.1016/j.bmcl.2011.10.033 BindingDB Entry DOI: 10.7270/Q27945PF
					More data for this Ligand-Target Pair
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50379177 (CHEMBL2010834) Show SMILES CNC(=O)c1ccc(CC(=O)N(C)C2CCN(Cc3ccc(cc3)C(F)(F)F)CC2)cc1 Show InChI InChI=1S/C24H28F3N3O2/c1-28-23(32)19-7-3-17(4-8-19)15-22(31)29(2)21-11-13-30(14-12-21)16-18-5-9-20(10-6-18)24(25,26)27/h3-10,21H,11-16H2,1-2H3,(H,28,32)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	489	n/a	n/a	n/a	n/a
Astrazeneca U K Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 receptor expressed in HEK293 cells assessed as cAMP accumulation after 45 mins by fluorescence assay				Bioorg Med Chem Lett 21: 7310-6 (2011) Article DOI: 10.1016/j.bmcl.2011.10.033 BindingDB Entry DOI: 10.7270/Q27945PF
					More data for this Ligand-Target Pair