BDBM50379187 CHEMBL2010878

SMILES: CC(C)n1c2ccc(Nc3ccncc3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12

InChI Key: InChIKey=CZEMFIDTCSFUMQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50379187   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50379187 (CHEMBL2010878) Show SMILES CC(C)n1c2ccc(Nc3ccncc3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12 Show InChI InChI=1S/C28H26N6O/c1-15(2)34-23-7-4-17(31-16-8-10-29-11-9-16)12-19(23)25-20-13-30-28(35)26(20)24-18(27(25)34)5-6-22-21(24)14-33(3)32-22/h4,7-12,14-15H,5-6,13H2,1-3H3,(H,29,31)(H,30,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	256	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGF-R2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluore...				J Med Chem 55: 903-13 (2012) Article DOI: 10.1021/jm201449n BindingDB Entry DOI: 10.7270/Q2ZS2XHW
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50379187 (CHEMBL2010878) Show SMILES CC(C)n1c2ccc(Nc3ccncc3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12 Show InChI InChI=1S/C28H26N6O/c1-15(2)34-23-7-4-17(31-16-8-10-29-11-9-16)12-19(23)25-20-13-30-28(35)26(20)24-18(27(25)34)5-6-22-21(24)14-33(3)32-22/h4,7-12,14-15H,5-6,13H2,1-3H3,(H,29,31)(H,30,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Tie2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluoresce...				J Med Chem 55: 903-13 (2012) Article DOI: 10.1021/jm201449n BindingDB Entry DOI: 10.7270/Q2ZS2XHW
					More data for this Ligand-Target Pair