null
SMILES: Cc1cc(O)cc(O)c1C(=O)O[C@H]1[C@@H]2COC(\C=C\CO)=CC2=CC(=O)[C@@]1(C)O
InChI Key: InChIKey=KKSKNERURMTALE-XWEVTOJWSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA polymerase delta catalytic subunit (Homo sapiens (Human)) | BDBM50379294 (CHEMBL2011647) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.64E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase delta assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins | J Nat Prod 75: 135-41 (2012) Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inosine-5'-monophosphate dehydrogenase 2 (Mus musculus) | BDBM50379294 (CHEMBL2011647) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of mouse IMP dehydrogenase 2 | J Nat Prod 75: 135-41 (2012) Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase beta (Rattus norvegicus) | BDBM50379294 (CHEMBL2011647) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of rat DNA polymerase beta expressed in Escherichia coli JMpbeta5 assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)1... | J Nat Prod 75: 135-41 (2012) Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed DNA/RNA polymerase mu (Homo sapiens (Human)) | BDBM50379294 (CHEMBL2011647) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human His-tagged recombinant DNA polymerase mu expressed in Escherichia coli BL21 assessed as inhibition of incorporation of dTTP into ... | J Nat Prod 75: 135-41 (2012) Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA nucleotidylexotransferase (Bos taurus) | BDBM50379294 (CHEMBL2011647) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of calf TdT assessed as inhibition of incorporation of dTTP into oligo(dT)18(3'OH) after 60 mins | J Nat Prod 75: 135-41 (2012) Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase nu (Homo sapiens (Human)) | BDBM50379294 (CHEMBL2011647) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.21E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of C-terminal-His6-tagged human pol nu expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(d... | J Nat Prod 75: 135-41 (2012) Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable maltase-glucoamylase 2 (Homo sapiens) | BDBM50379294 (CHEMBL2011647) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hebei University Curated by ChEMBL | Assay Description Inhibition of alpha-glucosidase (unknown origin) using p-nitrophenyl glycoside as substrate treated 20 mins post substrate addition measured for 1 mi... | J Nat Prod 80: 2199-2203 (2017) Article DOI: 10.1021/acs.jnatprod.7b00032 BindingDB Entry DOI: 10.7270/Q20P12MS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase kappa (Homo sapiens (Human)) | BDBM50379294 (CHEMBL2011647) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.89E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into po... | J Nat Prod 75: 135-41 (2012) Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed DNA polymerase (Enterobacteria phage T4) | BDBM50379294 (CHEMBL2011647) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of T4 bacteriophage DNA polymerase assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins | J Nat Prod 75: 135-41 (2012) Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polynucleotide kinase (Enterobacteria phage T4) | BDBM50379294 (CHEMBL2011647) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of T4 arnN8l pseT 1 polynucleotide kinase assessed as inhibition of Salmon sperm DNA phosphorylation using [gamma32P]ATP by liquid scintil... | J Nat Prod 75: 135-41 (2012) Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Deoxyribonuclease-1 (Bos taurus) | BDBM50379294 (CHEMBL2011647) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of bovine deoxyribonuclease 1 using [3H]-labelled DNA after 30 mins by agorose gel electrophoresis | J Nat Prod 75: 135-41 (2012) Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase lambda (Homo sapiens (Human)) | BDBM50379294 (CHEMBL2011647) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of human recombinant His-tagged DNA polymerase lambda expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into p... | J Nat Prod 75: 135-41 (2012) Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase iota (Mus musculus) | BDBM50379294 (CHEMBL2011647) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Science University of Tokyo Curated by ChEMBL | Assay Description Inhibition of mouse recombinant C-terminal-His6-tagged DNA polymerase iota assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 ... | J Nat Prod 75: 135-41 (2012) Article DOI: 10.1021/np200523b BindingDB Entry DOI: 10.7270/Q2T154NG | |||||||||||
More data for this Ligand-Target Pair |