Found 3 hits for monomerid = 50379415 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50379415
(CHEMBL2012029)Show InChI InChI=1S/C17H16N4O/c1-12-2-6-14(7-3-12)22-15-8-4-13(5-9-15)20-17-19-11-10-16(18)21-17/h2-11H,1H3,(H3,18,19,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description Displacement of dofetilide from human ERG |
Bioorg Med Chem Lett 22: 2033-42 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3 |
More data for this Ligand-Target Pair | |
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human)) | BDBM50379415
(CHEMBL2012029)Show InChI InChI=1S/C17H16N4O/c1-12-2-6-14(7-3-12)22-15-8-4-13(5-9-15)20-17-19-11-10-16(18)21-17/h2-11H,1H3,(H3,18,19,20,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description Antagonist activity at human partially inactivated NaV 1.5 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay |
Bioorg Med Chem Lett 22: 2033-42 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3 |
More data for this Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50379415
(CHEMBL2012029)Show InChI InChI=1S/C17H16N4O/c1-12-2-6-14(7-3-12)22-15-8-4-13(5-9-15)20-17-19-11-10-16(18)21-17/h2-11H,1H3,(H3,18,19,20,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description Antagonist activity at human partially inactivated NaV 1.7 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay |
Bioorg Med Chem Lett 22: 2033-42 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3 |
More data for this Ligand-Target Pair | |