Found 3 hits for monomerid = 50379490 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cyclin-dependent kinase 1
(Homo sapiens (Human)) | BDBM50379490
(CHEMBL2012399)Show InChI InChI=1S/C18H23N7O/c1-24-11-13(8-15(24)16(19)26)22-18-20-9-12-10-21-25(17(12)23-18)14-6-4-2-3-5-7-14/h8-11,14H,2-7H2,1H3,(H2,19,26)(H,20,22,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Biogen Idec Inc.
Curated by ChEMBL
| Assay Description Inhibition of CDK1 |
Bioorg Med Chem Lett 22: 2070-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.019 BindingDB Entry DOI: 10.7270/Q2833T1N |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50379490
(CHEMBL2012399)Show InChI InChI=1S/C18H23N7O/c1-24-11-13(8-15(24)16(19)26)22-18-20-9-12-10-21-25(17(12)23-18)14-6-4-2-3-5-7-14/h8-11,14H,2-7H2,1H3,(H2,19,26)(H,20,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
Biogen Idec Inc.
Curated by ChEMBL
| Assay Description Inhibition of aurora A kinase |
Bioorg Med Chem Lett 22: 2070-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.019 BindingDB Entry DOI: 10.7270/Q2833T1N |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50379490
(CHEMBL2012399)Show InChI InChI=1S/C18H23N7O/c1-24-11-13(8-15(24)16(19)26)22-18-20-9-12-10-21-25(17(12)23-18)14-6-4-2-3-5-7-14/h8-11,14H,2-7H2,1H3,(H2,19,26)(H,20,22,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Biogen Idec Inc.
Curated by ChEMBL
| Assay Description Inhibition of aurora B kinase |
Bioorg Med Chem Lett 22: 2070-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.019 BindingDB Entry DOI: 10.7270/Q2833T1N |
More data for this Ligand-Target Pair | |