BDBM50379513 CHEMBL2012566

SMILES: Cc1nccc2c3ccc(OC(C)(C)C)cc3n(CCCCN)c12

InChI Key: InChIKey=IPTQACFMCXUXER-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50379513   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual-specificity tyrosine-phosphorylation regulated kinase 2 (Homo sapiens (Human))	BDBM50379513 (CHEMBL2012566) Show SMILES Cc1nccc2c3ccc(OC(C)(C)C)cc3n(CCCCN)c12 Show InChI InChI=1S/C20H27N3O/c1-14-19-17(9-11-22-14)16-8-7-15(24-20(2,3)4)13-18(16)23(19)12-6-5-10-21/h7-9,11,13H,5-6,10,12,21H2,1-4H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of human N-terminal GST-tagged DYRK2 expressed in baculovirus using DYRKtide-F as substrate assessed as inhibition of [33P] incorporation ...				Bioorg Med Chem Lett 22: 2015-9 (2012) Article DOI: 10.1016/j.bmcl.2012.01.028 BindingDB Entry DOI: 10.7270/Q20K29KK
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50379513 (CHEMBL2012566) Show SMILES Cc1nccc2c3ccc(OC(C)(C)C)cc3n(CCCCN)c12 Show InChI InChI=1S/C20H27N3O/c1-14-19-17(9-11-22-14)16-8-7-15(24-20(2,3)4)13-18(16)23(19)12-6-5-10-21/h7-9,11,13H,5-6,10,12,21H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assay				Bioorg Med Chem Lett 22: 2015-9 (2012) Article DOI: 10.1016/j.bmcl.2012.01.028 BindingDB Entry DOI: 10.7270/Q20K29KK
					More data for this Ligand-Target Pair