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SMILES: COc1cccc2c3ccnc(C)c3n(CCCCN)c12

InChI Key: InChIKey=VXDUTCPSYSDXLA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50379516   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 2 (Homo sapiens (Human))	BDBM50379516 (CHEMBL2012569) Show SMILES COc1cccc2c3ccnc(C)c3n(CCCCN)c12 Show InChI InChI=1S/C17H21N3O/c1-12-16-14(8-10-19-12)13-6-5-7-15(21-2)17(13)20(16)11-4-3-9-18/h5-8,10H,3-4,9,11,18H2,1-2H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of human N-terminal GST-tagged DYRK2 expressed in baculovirus using DYRKtide-F as substrate assessed as inhibition of [33P] incorporation ...				Bioorg Med Chem Lett 22: 2015-9 (2012) Article DOI: 10.1016/j.bmcl.2012.01.028 BindingDB Entry DOI: 10.7270/Q20K29KK
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50379516 (CHEMBL2012569) Show SMILES COc1cccc2c3ccnc(C)c3n(CCCCN)c12 Show InChI InChI=1S/C17H21N3O/c1-12-16-14(8-10-19-12)13-6-5-7-15(21-2)17(13)20(16)11-4-3-9-18/h5-8,10H,3-4,9,11,18H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assay				Bioorg Med Chem Lett 22: 2015-9 (2012) Article DOI: 10.1016/j.bmcl.2012.01.028 BindingDB Entry DOI: 10.7270/Q20K29KK
					More data for this Ligand-Target Pair