BDBM50379614 CHEMBL2013048

SMILES: C1CC(C1)N1CCC2(CC1)CCc1cc(OC3CCNCC3)ccc1O2

InChI Key: InChIKey=IALVKGMYVHTORI-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50379614   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50379614 (CHEMBL2013048) Show SMILES C1CC(C1)N1CCC2(CC1)CCc1cc(OC3CCNCC3)ccc1O2 Show InChI InChI=1S/C22H32N2O2/c1-2-18(3-1)24-14-10-22(11-15-24)9-6-17-16-20(4-5-21(17)26-22)25-19-7-12-23-13-8-19/h4-5,16,18-19,23H,1-3,6-15H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in CHO cells				Bioorg Med Chem Lett 22: 2151-3 (2012) Article DOI: 10.1016/j.bmcl.2012.01.139 BindingDB Entry DOI: 10.7270/Q2736RX9
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50379614 (CHEMBL2013048) Show SMILES C1CC(C1)N1CCC2(CC1)CCc1cc(OC3CCNCC3)ccc1O2 Show InChI InChI=1S/C22H32N2O2/c1-2-18(3-1)24-14-10-22(11-15-24)9-6-17-16-20(4-5-21(17)26-22)25-19-7-12-23-13-8-19/h4-5,16,18-19,23H,1-3,6-15H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from rat cloned histamine H3 receptor expressed in CHO cells				Bioorg Med Chem Lett 22: 2151-3 (2012) Article DOI: 10.1016/j.bmcl.2012.01.139 BindingDB Entry DOI: 10.7270/Q2736RX9
					More data for this Ligand-Target Pair