Found 3 hits for monomerid = 50379628 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50379628
(CHEMBL2011330)Show InChI InChI=1S/C18H20N6S/c1-13-2-3-14(11-21-13)16-12-22-18(25-16)23-17-10-15(4-5-20-17)24-8-6-19-7-9-24/h2-5,10-12,19H,6-9H2,1H3,(H,20,22,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of CHK1 by time resolved fluorescence assay |
Bioorg Med Chem Lett 22: 2613-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.120 BindingDB Entry DOI: 10.7270/Q23B615X |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Cyclin-dependent kinase 7
(Homo sapiens (Human)) | BDBM50379628
(CHEMBL2011330)Show InChI InChI=1S/C18H20N6S/c1-13-2-3-14(11-21-13)16-12-22-18(25-16)23-17-10-15(4-5-20-17)24-8-6-19-7-9-24/h2-5,10-12,19H,6-9H2,1H3,(H,20,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of CDK7 |
Bioorg Med Chem Lett 22: 2613-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.120 BindingDB Entry DOI: 10.7270/Q23B615X |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50379628
(CHEMBL2011330)Show InChI InChI=1S/C18H20N6S/c1-13-2-3-14(11-21-13)16-12-22-18(25-16)23-17-10-15(4-5-20-17)24-8-6-19-7-9-24/h2-5,10-12,19H,6-9H2,1H3,(H,20,22,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Competitive inhibition of Chk1 in presence of higher ATP levels |
Bioorg Med Chem Lett 22: 2609-12 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.110 BindingDB Entry DOI: 10.7270/Q22F7PFG |
More data for this Ligand-Target Pair | 3D Structure (docked) |