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SMILES: Oc1ccc2nc([nH]c2c1CNCc1cccs1)-c1cccc(F)c1F

InChI Key: InChIKey=ZWEBWLOUGLXDPI-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50379677   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens (Human))		BDBM50379677
PNG
(CHEMBL2013205)
Show SMILES Oc1ccc2nc([nH]c2c1CNCc1cccs1)-c1cccc(F)c1F
Show InChI InChI=1S/C19H15F2N3OS/c20-14-5-1-4-12(17(14)21)19-23-15-6-7-16(25)13(18(15)24-19)10-22-9-11-3-2-8-26-11/h1-8,22,25H,9-10H2,(H,23,24)
PDB
MMDB

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KEGG

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 631n/an/an/an/an/an/a



GlaxoSmithKline R&D

Curated by ChEMBL


Assay Description
Displacement of [3H]-Ro256981 from human NR2B receptor

Bioorg Med Chem Lett 22: 2620-3 (2012)


Article DOI: 10.1016/j.bmcl.2012.01.108
BindingDB Entry DOI: 10.7270/Q2KD1ZX3
More data for this
Ligand-Target Pair