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SMILES: OC(=O)c1sc(N2CCOCC2)c(C#N)c1-c1ccc(Cl)cc1

InChI Key: InChIKey=IWFAAPXIFCDNDX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50380317   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))		BDBM50380317
PNG
(CHEMBL570592)
Show SMILES OC(=O)c1sc(N2CCOCC2)c(C#N)c1-c1ccc(Cl)cc1
Show InChI InChI=1S/C16H13ClN2O3S/c17-11-3-1-10(2-4-11)13-12(9-18)15(23-14(13)16(20)21)19-5-7-22-8-6-19/h1-4H,5-8H2,(H,20,21)
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Article
PubMed
 230n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PI3Kalpha

ACS Med Chem Lett 2: 809-813 (2011)


Article DOI: 10.1021/ml200126j
BindingDB Entry DOI: 10.7270/Q2DJ5GN2
More data for this
Ligand-Target Pair