BDBM50380760 CHEMBL2017979
SMILES: COc1cc(OC2CCN(CC2)S(C)(=O)=O)ccc1CC(=O)N1CCC(CC1)N1C(=O)CCc2ccccc12
InChI Key: InChIKey=FAVRBEXAAWYPRQ-UHFFFAOYSA-N
Data: 6 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Oxytocin receptor (Microtus ochrogaster) | BDBM50380760 (CHEMBL2017979) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Displacement of [125I]-OVTA from prairie vole Oxytocin receptor after 72 hrs | Bioorg Med Chem 20: 2721-38 (2012) Article DOI: 10.1016/j.bmc.2012.02.019 BindingDB Entry DOI: 10.7270/Q29K4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxytocin receptor (Homo sapiens (Human)) | BDBM50380760 (CHEMBL2017979) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Displacement of [3H]oxytocin from human oxytocin receptor after 1.5 hrs by liquid scintillation counting | Bioorg Med Chem 20: 2721-38 (2012) Article DOI: 10.1016/j.bmc.2012.02.019 BindingDB Entry DOI: 10.7270/Q29K4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V1a receptor (Microtus ochrogaster) | BDBM50380760 (CHEMBL2017979) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 78 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Displacement of [125I]-LVA from prairie vole vasopressin V1A receptor after 72 hrs | Bioorg Med Chem 20: 2721-38 (2012) Article DOI: 10.1016/j.bmc.2012.02.019 BindingDB Entry DOI: 10.7270/Q29K4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V1b receptor (Homo sapiens (Human)) | BDBM50380760 (CHEMBL2017979) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Displacement of [3H]-AVP from human V1b receptor after 1.5 hrs by liquid scintillation counting | Bioorg Med Chem 20: 2721-38 (2012) Article DOI: 10.1016/j.bmc.2012.02.019 BindingDB Entry DOI: 10.7270/Q29K4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50380760 (CHEMBL2017979) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Displacement of [3H]-AVP from human vasopressin V2 receptor after 1.5 hrs by liquid scintillation counting | Bioorg Med Chem 20: 2721-38 (2012) Article DOI: 10.1016/j.bmc.2012.02.019 BindingDB Entry DOI: 10.7270/Q29K4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V1a receptor (Homo sapiens (Human)) | BDBM50380760 (CHEMBL2017979) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Displacement of [3H]-AVP from human V1A receptor after 1.5 hrs by liquid scintillation counting | Bioorg Med Chem 20: 2721-38 (2012) Article DOI: 10.1016/j.bmc.2012.02.019 BindingDB Entry DOI: 10.7270/Q29K4C7G | |||||||||||
More data for this Ligand-Target Pair |