null

SMILES: CCn1cc(cn1)-c1cccc(c1)-c1cnc(N)c(n1)C(=O)N[C@H]1C2CC3CC1C[C@](O)(C3)C2

InChI Key: InChIKey=QSRWJNLAANDJCZ-IWPBWAMJSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50380766   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50380766 (CHEMBL2018146) Show SMILES CCn1cc(cn1)-c1cccc(c1)-c1cnc(N)c(n1)C(=O)N[C@H]1C2CC3CC1C[C@](O)(C3)C2 |r,wU:30.34,wD:23.25,TLB:31:30:23:27.25.26,22:23:29:27.26.32,THB:25:24:29:27.26.32,25:26:23.24.33:29,32:26:23:33.30.29,32:30:23:27.25.26,(-9.62,-2.09,;-8.88,-3.44,;-7.34,-3.48,;-6.41,-2.25,;-4.95,-2.76,;-4.99,-4.3,;-6.47,-4.74,;-3.68,-1.88,;-3.66,-.34,;-2.32,.41,;-1,-.37,;-1.01,-1.92,;-2.36,-2.67,;.3,-2.7,;.28,-4.25,;1.6,-5.03,;2.95,-4.28,;4.27,-5.06,;2.96,-2.73,;1.64,-1.95,;4.3,-1.97,;5.63,-2.76,;4.32,-.43,;5.64,.33,;7.15,.72,;8.54,.13,;9.58,1.39,;8.18,1.07,;6.86,1.58,;6.88,3.07,;8.23,3.52,;8.29,5.06,;9.62,2.92,;7.17,2.3,)| Show InChI InChI=1S/C26H30N6O2/c1-2-32-14-20(12-29-32)16-4-3-5-17(8-16)21-13-28-24(27)23(30-21)25(33)31-22-18-6-15-7-19(22)11-26(34,9-15)10-18/h3-5,8,12-15,18-19,22,34H,2,6-7,9-11H2,1H3,(H2,27,28)(H,31,33)/t15?,18?,19?,22-,26-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of human recombinant Sky using poly-GT as substrate and [33P]ATP after 40 mins by beta counting				Bioorg Med Chem Lett 22: 2784-8 (2012) Article DOI: 10.1016/j.bmcl.2012.02.087 BindingDB Entry DOI: 10.7270/Q25T3MHR
					More data for this Ligand-Target Pair