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SMILES: CC(C)(NC(=O)c1nc(cnc1N)-c1cccc(c1)-c1ccc(N)nc1)C1CCNCC1

InChI Key: InChIKey=PKLIOLRVZJABQL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50380784   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase receptor TYRO3


(Homo sapiens (Human))		BDBM50380784
PNG
(CHEMBL2018015)
Show SMILES CC(C)(NC(=O)c1nc(cnc1N)-c1cccc(c1)-c1ccc(N)nc1)C1CCNCC1
Show InChI InChI=1S/C24H29N7O/c1-24(2,18-8-10-27-11-9-18)31-23(32)21-22(26)29-14-19(30-21)16-5-3-4-15(12-16)17-6-7-20(25)28-13-17/h3-7,12-14,18,27H,8-11H2,1-2H3,(H2,25,28)(H2,26,29)(H,31,32)
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Similars
Article
PubMed
n/an/a 28n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of human recombinant Sky using poly-GT as substrate and [33P]ATP after 40 mins by beta counting

Bioorg Med Chem Lett 22: 2784-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.087
BindingDB Entry DOI: 10.7270/Q25T3MHR
More data for this
Ligand-Target Pair