BDBM50380883 CHEMBL2018965

SMILES: COc1cccc2n(Cc3cccc(CN(C)C(C)=O)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12

InChI Key: InChIKey=VCQBYDICCOARIN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50380883   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 4 (CCR4) (Homo sapiens (Human))	BDBM50380883 (CHEMBL2018965) Show SMILES COc1cccc2n(Cc3cccc(CN(C)C(C)=O)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12 Show InChI InChI=1S/C23H23ClN4O4S2/c1-15(29)27(2)13-16-6-4-7-17(12-16)14-28-18-8-5-9-19(32-3)22(18)23(25-28)26-34(30,31)21-11-10-20(24)33-21/h4-12H,13-14H2,1-3H3,(H,25,26)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	129	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR4 expressed in CHO membranes assessed as inhibition of [35S]-GTPgammaS binding by scintillation counting				Bioorg Med Chem Lett 22: 2730-3 (2012) Article DOI: 10.1016/j.bmcl.2012.02.104 BindingDB Entry DOI: 10.7270/Q2J38TK6
					More data for this Ligand-Target Pair