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BDBM50380917 CHEMBL2016734

SMILES: Fc1ccccc1-n1ccc(NC(=O)NC2CCC3(CC2)OC(=O)c2ccncc32)n1

InChI Key: InChIKey=KJAMUHYOZCKXHQ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50380917   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuropeptide Y receptor type 5 ( NPY Y5)


(Homo sapiens (Human))		BDBM50380917
PNG
(CHEMBL2016734)
Show SMILES Fc1ccccc1-n1ccc(NC(=O)NC2CCC3(CC2)OC(=O)c2ccncc32)n1 |(30.07,-39.3,;29.29,-40.63,;30.04,-41.97,;29.25,-43.3,;27.71,-43.28,;26.96,-41.94,;27.75,-40.61,;27,-39.27,;27.84,-37.98,;26.88,-36.77,;25.43,-37.32,;24.14,-36.47,;22.81,-37.26,;22.88,-38.8,;21.5,-36.45,;20.14,-37.19,;20.13,-38.73,;18.81,-39.49,;17.47,-38.72,;17.47,-37.18,;18.81,-36.42,;17.63,-40.26,;16.23,-40.88,;15.9,-42.39,;15.2,-39.73,;13.66,-39.73,;12.89,-38.4,;13.66,-37.07,;15.2,-37.07,;15.97,-38.4,;25.51,-38.86,)|
Show InChI InChI=1S/C22H20FN5O3/c23-17-3-1-2-4-18(17)28-12-8-19(27-28)26-21(30)25-14-5-9-22(10-6-14)16-13-24-11-7-15(16)20(29)31-22/h1-4,7-8,11-14H,5-6,9-10H2,(H2,25,26,27,30)
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UniChem

Similars
Article
PubMed
 849n/an/an/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in insect Sf9 membranes

Bioorg Med Chem Lett 22: 2738-43 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.098
BindingDB Entry DOI: 10.7270/Q2154J34
More data for this
Ligand-Target Pair