BDBM50380918 CHEMBL2016735

SMILES: CN([C@H]1CC[C@]2(CC1)OCc1ccccc21)C(=O)Nc1ccn(n1)-c1ccccc1F

InChI Key: InChIKey=UFWSAYGCUHFGGW-OWWJJEGGSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50380918   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50380918 (CHEMBL2016735) Show SMILES CN([C@H]1CC[C@]2(CC1)OCc1ccccc21)C(=O)Nc1ccn(n1)-c1ccccc1F |r,wU:2.1,5.8,(2.04,3.76,;2,2.21,;.65,1.48,;.64,-.06,;-.69,-.83,;-2.02,-.05,;-2.02,1.48,;-.69,2.25,;-1.86,-1.59,;-3.27,-2.21,;-4.29,-1.07,;-5.83,-1.06,;-6.6,.26,;-5.84,1.59,;-4.29,1.6,;-3.52,.27,;3.32,1.41,;3.39,-.13,;4.65,2.19,;5.94,1.34,;7.39,1.89,;8.35,.69,;7.5,-.6,;6.02,-.19,;8.26,-1.95,;7.46,-3.27,;8.22,-4.62,;9.76,-4.64,;10.55,-3.3,;9.79,-1.96,;10.58,-.64,)| Show InChI InChI=1S/C24H25FN4O2/c1-28(18-10-13-24(14-11-18)19-7-3-2-6-17(19)16-31-24)23(30)26-22-12-15-29(27-22)21-9-5-4-8-20(21)25/h2-9,12,15,18H,10-11,13-14,16H2,1H3,(H,26,27,30)/t18-,24+	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in insect Sf9 membranes				Bioorg Med Chem Lett 22: 2738-43 (2012) Article DOI: 10.1016/j.bmcl.2012.02.098 BindingDB Entry DOI: 10.7270/Q2154J34
					More data for this Ligand-Target Pair