BDBM50380919 CHEMBL2016736

SMILES: CN([C@H]1CC[C@@]2(COc3ccccc23)CC1)C(=O)Nc1ccn(n1)-c1ccccc1F

InChI Key: InChIKey=NXMMWFXEQNBGJS-WVQHILGCSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50380919   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50380919 (CHEMBL2016736) Show SMILES CN([C@H]1CC[C@@]2(COc3ccccc23)CC1)C(=O)Nc1ccn(n1)-c1ccccc1F |r,wU:2.1,5.5,(26.05,3.87,;26.01,2.33,;24.66,1.59,;24.65,.06,;23.33,-.71,;21.99,.06,;22.15,-1.47,;20.74,-2.1,;19.72,-.95,;18.18,-.95,;17.41,.38,;18.18,1.71,;19.72,1.72,;20.49,.38,;21.99,1.6,;23.33,2.37,;27.33,1.53,;27.4,-.02,;28.66,2.31,;29.95,1.46,;31.4,2.01,;32.36,.81,;31.52,-.48,;30.03,-.08,;32.27,-1.83,;31.48,-3.15,;32.23,-4.5,;33.77,-4.52,;34.56,-3.19,;33.81,-1.85,;34.59,-.52,)| Show InChI InChI=1S/C24H25FN4O2/c1-28(17-10-13-24(14-11-17)16-31-21-9-5-2-6-18(21)24)23(30)26-22-12-15-29(27-22)20-8-4-3-7-19(20)25/h2-9,12,15,17H,10-11,13-14,16H2,1H3,(H,26,27,30)/t17-,24-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in insect Sf9 membranes				Bioorg Med Chem Lett 22: 2738-43 (2012) Article DOI: 10.1016/j.bmcl.2012.02.098 BindingDB Entry DOI: 10.7270/Q2154J34
					More data for this Ligand-Target Pair