BDBM50380921 CHEMBL2016738

SMILES: CN([C@H]1CC[C@@]2(CC1)Cc1cnccc1C(=O)O2)C(=O)Nc1ccn(n1)-c1ccccc1F

InChI Key: InChIKey=CXATWLVOEUMHKK-SMQSCJQKSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50380921   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50380921 (CHEMBL2016738) Show SMILES CN([C@H]1CC[C@@]2(CC1)Cc1cnccc1C(=O)O2)C(=O)Nc1ccn(n1)-c1ccccc1F |r,wU:2.1,5.19,(24.41,-6.79,;24.37,-8.33,;23.01,-9.07,;23.01,-10.61,;21.68,-11.37,;20.35,-10.6,;20.34,-9.07,;21.68,-8.3,;19.01,-9.83,;17.69,-10.6,;16.36,-9.83,;15.02,-10.59,;15.02,-12.14,;16.35,-12.9,;17.68,-12.14,;19.02,-12.91,;19.02,-14.45,;20.36,-12.14,;25.68,-9.14,;25.75,-10.68,;27.01,-8.36,;28.29,-9.2,;29.74,-8.65,;30.7,-9.86,;29.86,-11.14,;28.37,-10.74,;30.61,-12.49,;29.82,-13.81,;30.57,-15.15,;32.11,-15.18,;32.9,-13.84,;32.15,-12.51,;32.93,-11.18,)| Show InChI InChI=1S/C24H24FN5O3/c1-29(23(32)27-21-9-13-30(28-21)20-5-3-2-4-19(20)25)17-6-10-24(11-7-17)14-16-15-26-12-8-18(16)22(31)33-24/h2-5,8-9,12-13,15,17H,6-7,10-11,14H2,1H3,(H,27,28,32)/t17-,24+	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	188	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in insect Sf9 membranes				Bioorg Med Chem Lett 22: 2738-43 (2012) Article DOI: 10.1016/j.bmcl.2012.02.098 BindingDB Entry DOI: 10.7270/Q2154J34
					More data for this Ligand-Target Pair