BDBM50380925 CHEMBL2016742

SMILES: CN([C@H]1CC[C@@]2(CC1)Cc1ccccc1C(=O)O2)C(=O)Nc1cnc(cn1)-c1ccccc1

InChI Key: InChIKey=APWJYBHZNGCNDH-ZVWHWTBFSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50380925   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50380925 (CHEMBL2016742) Show SMILES CN([C@H]1CC[C@@]2(CC1)Cc1ccccc1C(=O)O2)C(=O)Nc1cnc(cn1)-c1ccccc1 |r,wU:2.1,5.19,(28.87,3.24,;28.83,1.7,;27.47,.96,;27.47,-.58,;26.14,-1.34,;24.81,-.57,;24.8,.97,;26.14,1.73,;23.47,.2,;22.15,-.57,;20.82,.2,;19.48,-.56,;19.48,-2.11,;20.81,-2.87,;22.14,-2.11,;23.48,-2.88,;23.48,-4.42,;24.82,-2.11,;30.14,.89,;30.21,-.65,;31.47,1.68,;32.81,.92,;34.14,1.69,;35.47,.92,;35.48,-.62,;34.14,-1.4,;32.81,-.62,;36.81,-1.39,;36.81,-2.94,;38.15,-3.71,;39.48,-2.93,;39.47,-1.38,;38.14,-.62,)| Show InChI InChI=1S/C26H26N4O3/c1-30(25(32)29-23-17-27-22(16-28-23)18-7-3-2-4-8-18)20-11-13-26(14-12-20)15-19-9-5-6-10-21(19)24(31)33-26/h2-10,16-17,20H,11-15H2,1H3,(H,28,29,32)/t20-,26+	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in insect Sf9 membranes				Bioorg Med Chem Lett 22: 2738-43 (2012) Article DOI: 10.1016/j.bmcl.2012.02.098 BindingDB Entry DOI: 10.7270/Q2154J34
					More data for this Ligand-Target Pair