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BDBM50380926 CHEMBL2016743

SMILES: CCN([C@H]1CC[C@@]2(CC1)Cc1ccccc1C(=O)O2)C(=O)Nc1cnc(cn1)-c1ccccc1

InChI Key: InChIKey=KPKHQVBMIDIXAG-ZSQTZEJBSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50380926   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuropeptide Y receptor type 5 ( NPY Y5)


(Homo sapiens (Human))		BDBM50380926
PNG
(CHEMBL2016743)
Show SMILES CCN([C@H]1CC[C@@]2(CC1)Cc1ccccc1C(=O)O2)C(=O)Nc1cnc(cn1)-c1ccccc1 |r,wU:3.2,6.20,(-.27,-8.96,;1.04,-9.76,;1,-11.3,;-.35,-12.04,;-.36,-13.58,;-1.68,-14.34,;-3.01,-13.57,;-3.02,-12.03,;-1.68,-11.27,;-4.35,-12.8,;-5.67,-13.57,;-7,-12.8,;-8.34,-13.56,;-8.34,-15.11,;-7.01,-15.88,;-5.68,-15.11,;-4.34,-15.88,;-4.34,-17.42,;-3,-15.11,;2.32,-12.11,;2.39,-13.65,;3.65,-11.33,;4.99,-12.08,;6.32,-11.31,;7.65,-12.08,;7.65,-13.62,;6.32,-14.4,;4.98,-13.63,;8.99,-14.39,;8.99,-15.94,;10.32,-16.71,;11.66,-15.93,;11.65,-14.38,;10.32,-13.62,)|
Show InChI InChI=1S/C27H28N4O3/c1-2-31(26(33)30-24-18-28-23(17-29-24)19-8-4-3-5-9-19)21-12-14-27(15-13-21)16-20-10-6-7-11-22(20)25(32)34-27/h3-11,17-18,21H,2,12-16H2,1H3,(H,29,30,33)/t21-,27+
KEGG

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Article
PubMed
 11n/an/an/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in insect Sf9 membranes

Bioorg Med Chem Lett 22: 2738-43 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.098
BindingDB Entry DOI: 10.7270/Q2154J34
More data for this
Ligand-Target Pair