BDBM50381022 CHEMBL2017139
SMILES: CCCCCCCCCCCCCCCCCC(=O)OCC(COP(O)(S)=O)OC
InChI Key: InChIKey=AYKYANCQUONAPE-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Lysophosphatidic acid receptor 6 (Homo sapiens (Human)) | BDBM50381022 (CHEMBL2017139) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 86 | n/a | n/a | n/a | n/a |
The University of Utah Curated by ChEMBL | Assay Description Agonist activity at human LPA6 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 | Bioorg Med Chem Lett 23: 1865-9 (2013) Article DOI: 10.1016/j.bmcl.2013.01.002 BindingDB Entry DOI: 10.7270/Q2SN0B9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 5 (LPA5) (Homo sapiens (Human)) | BDBM50381022 (CHEMBL2017139) | UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a |
The University of Utah Curated by ChEMBL | Assay Description Agonist activity at human LPA5 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 | Bioorg Med Chem Lett 23: 1865-9 (2013) Article DOI: 10.1016/j.bmcl.2013.01.002 BindingDB Entry DOI: 10.7270/Q2SN0B9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 4 (Homo sapiens (Human)) | BDBM50381022 (CHEMBL2017139) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a |
The University of Utah Curated by ChEMBL | Assay Description Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 | Bioorg Med Chem Lett 23: 1865-9 (2013) Article DOI: 10.1016/j.bmcl.2013.01.002 BindingDB Entry DOI: 10.7270/Q2SN0B9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human)) | BDBM50381022 (CHEMBL2017139) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Technical University of Lodz Curated by ChEMBL | Assay Description Inhibition of human recombinant autotaxin expressed in insect Sf9 cells using FS-3 as substrate preincubated for 10 mins prior substrate addition mea... | Bioorg Med Chem Lett 22: 2698-700 (2012) Article DOI: 10.1016/j.bmcl.2012.03.008 BindingDB Entry DOI: 10.7270/Q27P90DG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor Edg-4 (Homo sapiens (Human)) | BDBM50381022 (CHEMBL2017139) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 161 | n/a | n/a | n/a | n/a |
The University of Utah Curated by ChEMBL | Assay Description Agonist activity at human LPA2 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay | Bioorg Med Chem Lett 23: 1865-9 (2013) Article DOI: 10.1016/j.bmcl.2013.01.002 BindingDB Entry DOI: 10.7270/Q2SN0B9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 1 (Homo sapiens (Human)) | BDBM50381022 (CHEMBL2017139) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 17 | n/a | n/a | n/a | n/a |
The University of Utah Curated by ChEMBL | Assay Description Agonist activity at human LPA1 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay | Bioorg Med Chem Lett 23: 1865-9 (2013) Article DOI: 10.1016/j.bmcl.2013.01.002 BindingDB Entry DOI: 10.7270/Q2SN0B9G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysophosphatidic acid receptor 3 (LPAR3) (Homo sapiens (Human)) | BDBM50381022 (CHEMBL2017139) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.280 | n/a | n/a | n/a | n/a |
The University of Utah Curated by ChEMBL | Assay Description Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay | Bioorg Med Chem Lett 23: 1865-9 (2013) Article DOI: 10.1016/j.bmcl.2013.01.002 BindingDB Entry DOI: 10.7270/Q2SN0B9G | |||||||||||
More data for this Ligand-Target Pair |