BDBM50381108 CHEMBL2017708
SMILES: Fc1ccc(cc1)-c1nc(Nc2ccn[nH]2)c2ccccc2n1
InChI Key: InChIKey=REUDMXPMMLBGBT-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase pknB (Mycobacterium tuberculosis) | BDBM50381108 (CHEMBL2017708) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 453 | n/a | n/a | n/a | n/a | n/a | n/a |
MRC Technology Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis GST-fused PknB expressed in Escherichia coli assessed as GarA substrate phosphorylation after 30 mins | Bioorg Med Chem Lett 22: 3349-53 (2012) Article DOI: 10.1016/j.bmcl.2012.02.107 BindingDB Entry DOI: 10.7270/Q22Z16JX | |||||||||||
More data for this Ligand-Target Pair |