BDBM50381112 CHEMBL2017712
SMILES: C1CC1c1cc(Nc2nc(NC3CCCCC3)nc3ccccc23)[nH]n1
InChI Key: InChIKey=BMZPYOBSEOUYRV-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase pknB (Mycobacterium tuberculosis) | BDBM50381112 (CHEMBL2017712) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 107 | n/a | n/a | n/a | n/a | n/a | n/a |
MRC Technology Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis GST-fused PknB expressed in Escherichia coli assessed as GarA substrate phosphorylation after 30 mins | Bioorg Med Chem Lett 22: 3349-53 (2012) Article DOI: 10.1016/j.bmcl.2012.02.107 BindingDB Entry DOI: 10.7270/Q22Z16JX | |||||||||||
More data for this Ligand-Target Pair |