BDBM50381288 CHEMBL2019021

SMILES: COc1cc(N)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1

InChI Key: InChIKey=DNHMCBAUCKMZOU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50381288   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 7B (Homo sapiens (Human))	BDBM50381288 (CHEMBL2019021) Show SMILES COc1cc(N)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 Show InChI InChI=1S/C18H20N4O2S/c1-24-13-9-11(19)7-8-12(13)16-20-17(23)14-15(22-25-18(14)21-16)10-5-3-2-4-6-10/h7-10H,2-6,19H2,1H3,(H,20,21,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Glenmark Pharmaceuticals Limited Curated by ChEMBL					Assay Description Displacement of [3H]-cAMP from human recombinant PDE7B				Bioorg Med Chem Lett 22: 3223-8 (2012) Article DOI: 10.1016/j.bmcl.2012.03.025 BindingDB Entry DOI: 10.7270/Q2NP25F2
					More data for this Ligand-Target Pair
Phosphodiesterase 7 (Homo sapiens (Human))	BDBM50381288 (CHEMBL2019021) Show SMILES COc1cc(N)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 Show InChI InChI=1S/C18H20N4O2S/c1-24-13-9-11(19)7-8-12(13)16-20-17(23)14-15(22-25-18(14)21-16)10-5-3-2-4-6-10/h7-10H,2-6,19H2,1H3,(H,20,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Glenmark Pharmaceuticals Limited Curated by ChEMBL					Assay Description Displacement of [3H]-cAMP from human recombinant PDE7A				Bioorg Med Chem Lett 22: 3223-8 (2012) Article DOI: 10.1016/j.bmcl.2012.03.025 BindingDB Entry DOI: 10.7270/Q2NP25F2
					More data for this Ligand-Target Pair