BDBM50381918 CHEMBL2023113
SMILES: NC(=O)C1(CCC1)c1cccc2Nc3nc(ccc3CN(c12)S(=O)(=O)c1ccc(OC(F)(F)F)cc1)C(F)(F)F
InChI Key: InChIKey=PWTPGXHAPNAWJN-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bombesin receptor subtype-3 (Mus musculus) | BDBM50381918 (CHEMBL2023113) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 22 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Agonist activity at mouse BRS3 expressed in human HEK293AEQ cells measured for 10 mins by aequorin bioluminescence assay | Bioorg Med Chem 20: 2845-9 (2012) Article DOI: 10.1016/j.bmc.2012.03.029 BindingDB Entry DOI: 10.7270/Q2F190R8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BRS3 (Homo sapiens (Human)) | BDBM50381918 (CHEMBL2023113) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Agonist activity at human BRS3 expressed in human HEK293AEQ cells measured for 10 mins by aequorin bioluminescence assay | Bioorg Med Chem 20: 2845-9 (2012) Article DOI: 10.1016/j.bmc.2012.03.029 BindingDB Entry DOI: 10.7270/Q2F190R8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BRS3 (Homo sapiens (Human)) | BDBM50381918 (CHEMBL2023113) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of 125I-dY-peptide from human BRS3 expressed in NFAT-CHO cells after 2 hrs by liquid scintillation counting | Bioorg Med Chem 20: 2845-9 (2012) Article DOI: 10.1016/j.bmc.2012.03.029 BindingDB Entry DOI: 10.7270/Q2F190R8 | |||||||||||
More data for this Ligand-Target Pair |