BDBM50382046 CHEMBL2022737

SMILES: Fc1ccccc1C(=O)Nc1ccc(-c2nnc(NCCCCN3CCCCC3)o2)c(Cl)c1

InChI Key: InChIKey=NSZFUYCPGKECED-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50382046   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50382046 (CHEMBL2022737) Show SMILES Fc1ccccc1C(=O)Nc1ccc(-c2nnc(NCCCCN3CCCCC3)o2)c(Cl)c1 Show InChI InChI=1S/C24H27ClFN5O2/c25-20-16-17(28-22(32)19-8-2-3-9-21(19)26)10-11-18(20)23-29-30-24(33-23)27-12-4-7-15-31-13-5-1-6-14-31/h2-3,8-11,16H,1,4-7,12-15H2,(H,27,30)(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]Dofetilide from human ERG expressed in CHO-K1 cells by scintillation proximity assay				Bioorg Med Chem Lett 22: 3531-4 (2012) Article DOI: 10.1016/j.bmcl.2012.03.062 BindingDB Entry DOI: 10.7270/Q2SB46SH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50382046 (CHEMBL2022737) Show SMILES Fc1ccccc1C(=O)Nc1ccc(-c2nnc(NCCCCN3CCCCC3)o2)c(Cl)c1 Show InChI InChI=1S/C24H27ClFN5O2/c25-20-16-17(28-22(32)19-8-2-3-9-21(19)26)10-11-18(20)23-29-30-24(33-23)27-12-4-7-15-31-13-5-1-6-14-31/h2-3,8-11,16H,1,4-7,12-15H2,(H,27,30)(H,28,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	39.8	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at human alpha7 nAChR expressed in GH4C1 cells by FLIPR assay				Bioorg Med Chem Lett 22: 3531-4 (2012) Article DOI: 10.1016/j.bmcl.2012.03.062 BindingDB Entry DOI: 10.7270/Q2SB46SH
					More data for this Ligand-Target Pair