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BDBM50382165 CHEMBL2023823

SMILES: CN1CCN(CC1)c1ccc(cc1)C(c1ccccc1)C12CC3CC(CC(C3)C1)C2

InChI Key: InChIKey=ZLOIGSNUNDZINZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50382165   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50382165
PNG
(CHEMBL2023823)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(c1ccccc1)C12CC3CC(CC(C3)C1)C2 |TLB:13:20:23.22.27:25,THB:21:22:25:29.20.28,21:20:23.22.27:25,28:20:23:27.26.25,28:26:23:29.21.20,13:20:23:27.26.25|
Show InChI InChI=1S/C28H36N2/c1-29-11-13-30(14-12-29)26-9-7-25(8-10-26)27(24-5-3-2-4-6-24)28-18-21-15-22(19-28)17-23(16-21)20-28/h2-10,21-23,27H,11-20H2,1H3
PDB

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.20n/an/an/an/an/an/a



National and Kapodistrian University of Athens

Curated by ChEMBL


Assay Description
Displacement of [3H](+)pentazocine from sigma-1 receptor expressed in human Jurkat cell membranes after 2 hrs by liquid scintillation spectroscopy

Bioorg Med Chem 20: 3323-31 (2012)


Article DOI: 10.1016/j.bmc.2012.03.038
BindingDB Entry DOI: 10.7270/Q20V8DT0
More data for this
Ligand-Target Pair