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SMILES: FC(F)(F)c1nc2cccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c2[nH]1

InChI Key: InChIKey=XYUBWZQJSZMHLF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50382232   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50382232
PNG
(CHEMBL2024660)
Show SMILES FC(F)(F)c1nc2cccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c2[nH]1
Show InChI InChI=1S/C16H9ClF6N4O/c17-9-5-4-7(6-8(9)15(18,19)20)24-14(28)26-11-3-1-2-10-12(11)27-13(25-10)16(21,22)23/h1-6H,(H,25,27)(H2,24,26,28)
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n/an/a 32n/an/an/an/an/an/a



Bayer Yakuhin, Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 expressed in CHOluc9aeq cells assessed as inhibition of capsaicin-stimulated response by aequorin and CRE-lucifear...

Bioorg Med Chem Lett 22: 3408-11 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.108
BindingDB Entry DOI: 10.7270/Q2C24XF7
More data for this
Ligand-Target Pair