BDBM50382243 CHEMBL2024492
SMILES: Oc1ccc2c(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cccc2c1
InChI Key: InChIKey=RYZUIEUNYFWFGL-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM50382243 (CHEMBL2024492) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Yakuhin, Ltd Curated by ChEMBL | Assay Description Antagonist activity at human TRPV1 expressed in CHOluc9aeq cells assessed as inhibition of capsaicin-stimulated response by aequorin and CRE-lucifear... | Bioorg Med Chem Lett 22: 3408-11 (2012) Article DOI: 10.1016/j.bmcl.2012.03.108 BindingDB Entry DOI: 10.7270/Q2C24XF7 | |||||||||||
More data for this Ligand-Target Pair |