BDBM50382438 CHEMBL2023346

SMILES: CN1CCN(Cc2ccc(Nc3ncc(Cl)c(n3)-c3ccc(F)cc3S(=O)(=O)N3CCCC3)cc2)CC1

InChI Key: InChIKey=RJDWEZHVKJPGPL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50382438   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50382438 (CHEMBL2023346) Show SMILES CN1CCN(Cc2ccc(Nc3ncc(Cl)c(n3)-c3ccc(F)cc3S(=O)(=O)N3CCCC3)cc2)CC1 Show InChI InChI=1S/C26H30ClFN6O2S/c1-32-12-14-33(15-13-32)18-19-4-7-21(8-5-19)30-26-29-17-23(27)25(31-26)22-9-6-20(28)16-24(22)37(35,36)34-10-2-3-11-34/h4-9,16-17H,2-3,10-15,18H2,1H3,(H,29,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged AXL kinase using fluorescein-labelled poly-GT as substrate after 60 mins by TR-FRET analysis				ACS Med Chem Lett 2: 907-912 (2011) Article DOI: 10.1021/ml200198x BindingDB Entry DOI: 10.7270/Q2DZ099R
					More data for this Ligand-Target Pair