null

SMILES: Cc1cccc(c1)C(CCCN)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=CYKPIMPUPKXTNO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50382558   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50382558 (CHEMBL2022997) Show SMILES Cc1cccc(c1)C(CCCN)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H25N/c1-19-10-8-15-22(18-19)23(16-9-17-24,20-11-4-2-5-12-20)21-13-6-3-7-14-21/h2-8,10-15,18H,9,16-17,24H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Beatson Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of human N-terminal His6-tagged Eg5 (1 to 368 amino acid residues) motor domain basal ATPase activity expressed in Escherichia coli BL21 (...				J Med Chem 56: 1878-93 (2013) Article DOI: 10.1021/jm3014597 BindingDB Entry DOI: 10.7270/Q20866NN
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50382558 (CHEMBL2022997) Show SMILES Cc1cccc(c1)C(CCCN)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H25N/c1-19-10-8-15-22(18-19)23(16-9-17-24,20-11-4-2-5-12-20)21-13-6-3-7-14-21/h2-8,10-15,18H,9,16-17,24H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Beatson Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of MT-stimulated human N-terminal His6-tagged Eg5 (1 to 368 amino acid residues) motor domain ATPase activity expressed in Escherichia col...				J Med Chem 56: 1878-93 (2013) Article DOI: 10.1021/jm3014597 BindingDB Entry DOI: 10.7270/Q20866NN
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50382558 (CHEMBL2022997) Show SMILES Cc1cccc(c1)C(CCCN)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H25N/c1-19-10-8-15-22(18-19)23(16-9-17-24,20-11-4-2-5-12-20)21-13-6-3-7-14-21/h2-8,10-15,18H,9,16-17,24H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Beatson Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of human ERG				J Med Chem 55: 1511-25 (2012) Article DOI: 10.1021/jm201195m BindingDB Entry DOI: 10.7270/Q2CZ386T
					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50382558 (CHEMBL2022997) Show SMILES Cc1cccc(c1)C(CCCN)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H25N/c1-19-10-8-15-22(18-19)23(16-9-17-24,20-11-4-2-5-12-20)21-13-6-3-7-14-21/h2-8,10-15,18H,9,16-17,24H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Beatson Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of CYP1A2				J Med Chem 55: 1511-25 (2012) Article DOI: 10.1021/jm201195m BindingDB Entry DOI: 10.7270/Q2CZ386T
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50382558 (CHEMBL2022997) Show SMILES Cc1cccc(c1)C(CCCN)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H25N/c1-19-10-8-15-22(18-19)23(16-9-17-24,20-11-4-2-5-12-20)21-13-6-3-7-14-21/h2-8,10-15,18H,9,16-17,24H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Beatson Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...				J Med Chem 55: 1511-25 (2012) Article DOI: 10.1021/jm201195m BindingDB Entry DOI: 10.7270/Q2CZ386T
					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50382558 (CHEMBL2022997) Show SMILES Cc1cccc(c1)C(CCCN)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H25N/c1-19-10-8-15-22(18-19)23(16-9-17-24,20-11-4-2-5-12-20)21-13-6-3-7-14-21/h2-8,10-15,18H,9,16-17,24H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Beatson Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of CYP2C19				J Med Chem 55: 1511-25 (2012) Article DOI: 10.1021/jm201195m BindingDB Entry DOI: 10.7270/Q2CZ386T
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50382558 (CHEMBL2022997) Show SMILES Cc1cccc(c1)C(CCCN)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H25N/c1-19-10-8-15-22(18-19)23(16-9-17-24,20-11-4-2-5-12-20)21-13-6-3-7-14-21/h2-8,10-15,18H,9,16-17,24H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Beatson Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of CYP2D6				J Med Chem 55: 1511-25 (2012) Article DOI: 10.1021/jm201195m BindingDB Entry DOI: 10.7270/Q2CZ386T
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50382558 (CHEMBL2022997) Show SMILES Cc1cccc(c1)C(CCCN)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H25N/c1-19-10-8-15-22(18-19)23(16-9-17-24,20-11-4-2-5-12-20)21-13-6-3-7-14-21/h2-8,10-15,18H,9,16-17,24H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Beatson Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of CYP3A4				J Med Chem 55: 1511-25 (2012) Article DOI: 10.1021/jm201195m BindingDB Entry DOI: 10.7270/Q2CZ386T
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50382558 (CHEMBL2022997) Show SMILES Cc1cccc(c1)C(CCCN)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H25N/c1-19-10-8-15-22(18-19)23(16-9-17-24,20-11-4-2-5-12-20)21-13-6-3-7-14-21/h2-8,10-15,18H,9,16-17,24H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Beatson Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...				J Med Chem 55: 1511-25 (2012) Article DOI: 10.1021/jm201195m BindingDB Entry DOI: 10.7270/Q2CZ386T
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50382558 (CHEMBL2022997) Show SMILES Cc1cccc(c1)C(CCCN)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H25N/c1-19-10-8-15-22(18-19)23(16-9-17-24,20-11-4-2-5-12-20)21-13-6-3-7-14-21/h2-8,10-15,18H,9,16-17,24H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Beatson Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of CYP2C9				J Med Chem 55: 1511-25 (2012) Article DOI: 10.1021/jm201195m BindingDB Entry DOI: 10.7270/Q2CZ386T
					More data for this Ligand-Target Pair