BDBM50382591 CHEMBL2022984

SMILES: CCCc1cccc(c1)C(SCCN)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=YCFSKQRZJMJUPV-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50382591   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50382591 (CHEMBL2022984) Show SMILES CCCc1cccc(c1)C(SCCN)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H27NS/c1-2-10-20-11-9-16-23(19-20)24(26-18-17-25,21-12-5-3-6-13-21)22-14-7-4-8-15-22/h3-9,11-16,19H,2,10,17-18,25H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Beatson Institute for Cancer Research Curated by ChEMBL					Assay Description Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...				J Med Chem 55: 1511-25 (2012) Article DOI: 10.1021/jm201195m BindingDB Entry DOI: 10.7270/Q2CZ386T
					More data for this Ligand-Target Pair