BDBM50383052 CHEMBL2031303

SMILES: CCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)CCN(C)C

InChI Key: InChIKey=VZTGBLZWTYWXAI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50383052   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50383052 (CHEMBL2031303) Show SMILES CCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)CCN(C)C Show InChI InChI=1S/C21H23ClFN5O2/c1-4-30-19-11-17-14(10-18(19)27-20(29)7-8-28(2)3)21(25-12-24-17)26-13-5-6-16(23)15(22)9-13/h5-6,9-12H,4,7-8H2,1-3H3,(H,27,29)(H,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.270	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis				J Med Chem 55: 2251-64 (2012) Article DOI: 10.1021/jm201507x BindingDB Entry DOI: 10.7270/Q20K29M1
					More data for this Ligand-Target Pair