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SMILES: COC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c1ccc(cc1)C(O)=O)c1ccccc21

InChI Key: InChIKey=GBDSDSSPYNQXEN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50383083   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kinesin-like protein KIF11


(Homo sapiens (Human))		BDBM50383083
PNG
(CHEMBL1551717)
Show SMILES COC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c1ccc(cc1)C(O)=O)c1ccccc21
Show InChI InChI=1S/C22H17NO7S/c1-12-19(22(26)29-2)17-11-18(15-5-3-4-6-16(15)20(17)30-12)23-31(27,28)14-9-7-13(8-10-14)21(24)25/h3-11,23H,1-2H3,(H,24,25)
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MMDB

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Article
PubMed
n/an/a 7.91E+4n/an/an/an/an/an/a



Korea Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of Eg5 ATPase activity by pyruvate kinase/lactate dehydrogenase-linked assay

J Med Chem 55: 2561-73 (2012)


Article DOI: 10.1021/jm201290v
BindingDB Entry DOI: 10.7270/Q2M909P0
More data for this
Ligand-Target Pair