BDBM50383119 CHEMBL2031742

SMILES: O=C1N(CCN2CCCC2)CCc2cc(ccc12)-c1ccccc1

InChI Key: InChIKey=GSAGTJUQXZNCBN-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50383119   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50383119 (CHEMBL2031742) Show SMILES O=C1N(CCN2CCCC2)CCc2cc(ccc12)-c1ccccc1 Show InChI InChI=1S/C21H24N2O/c24-21-20-9-8-18(17-6-2-1-3-7-17)16-19(20)10-13-23(21)15-14-22-11-4-5-12-22/h1-3,6-9,16H,4-5,10-15H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-(R)-alpha-methylhistamine from human H3 receptor expressed in HEK293T cells after 120 mins by scintillation counting				J Med Chem 55: 2452-68 (2012) Article DOI: 10.1021/jm300011d BindingDB Entry DOI: 10.7270/Q2736RZR
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50383119 (CHEMBL2031742) Show SMILES O=C1N(CCN2CCCC2)CCc2cc(ccc12)-c1ccccc1 Show InChI InChI=1S/C21H24N2O/c24-21-20-9-8-18(17-6-2-1-3-7-17)16-19(20)10-13-23(21)15-14-22-11-4-5-12-22/h1-3,6-9,16H,4-5,10-15H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	145	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-(R)-alpha-methylhistamine from rat H3 receptor expressed in HEK293T cells after 120 mins by scintillation counting				J Med Chem 55: 2452-68 (2012) Article DOI: 10.1021/jm300011d BindingDB Entry DOI: 10.7270/Q2736RZR
					More data for this Ligand-Target Pair