BDBM50383124 CHEMBL2031747

SMILES: O=C1N(CCN2CCCC2)CCc2cc(ccc12)-c1ccc(cc1)C#N

InChI Key: InChIKey=UQIRATJNZOMMRO-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50383124   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50383124 (CHEMBL2031747) Show SMILES O=C1N(CCN2CCCC2)CCc2cc(ccc12)-c1ccc(cc1)C#N Show InChI InChI=1S/C22H23N3O/c23-16-17-3-5-18(6-4-17)19-7-8-21-20(15-19)9-12-25(22(21)26)14-13-24-10-1-2-11-24/h3-8,15H,1-2,9-14H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-(R)-alpha-methylhistamine from human H3 receptor expressed in HEK293T cells after 120 mins by scintillation counting				J Med Chem 55: 2452-68 (2012) Article DOI: 10.1021/jm300011d BindingDB Entry DOI: 10.7270/Q2736RZR
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50383124 (CHEMBL2031747) Show SMILES O=C1N(CCN2CCCC2)CCc2cc(ccc12)-c1ccc(cc1)C#N Show InChI InChI=1S/C22H23N3O/c23-16-17-3-5-18(6-4-17)19-7-8-21-20(15-19)9-12-25(22(21)26)14-13-24-10-1-2-11-24/h3-8,15H,1-2,9-14H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-(R)-alpha-methylhistamine from rat H3 receptor expressed in HEK293T cells after 120 mins by scintillation counting				J Med Chem 55: 2452-68 (2012) Article DOI: 10.1021/jm300011d BindingDB Entry DOI: 10.7270/Q2736RZR
					More data for this Ligand-Target Pair