BDBM50383145 CHEMBL2031865

SMILES: O=C1N(CCN2CCCC2)CCc2cc(ccc12)-c1ccncc1

InChI Key: InChIKey=OYOUUSCAVHSQKA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50383145   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50383145 (CHEMBL2031865) Show SMILES O=C1N(CCN2CCCC2)CCc2cc(ccc12)-c1ccncc1 Show InChI InChI=1S/C20H23N3O/c24-20-19-4-3-17(16-5-8-21-9-6-16)15-18(19)7-12-23(20)14-13-22-10-1-2-11-22/h3-6,8-9,15H,1-2,7,10-14H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-(R)-alpha-methylhistamine from human H3 receptor expressed in HEK293T cells after 120 mins by scintillation counting				J Med Chem 55: 2452-68 (2012) Article DOI: 10.1021/jm300011d BindingDB Entry DOI: 10.7270/Q2736RZR
					More data for this Ligand-Target Pair