BDBM50383160 CHEMBL2031881

SMILES: CNC(=O)c1ccc(c(F)c1)-c1ccc2C(=O)N(CCN3CCCC3)CCc2c1

InChI Key: InChIKey=DABFIICBZLUPJU-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50383160   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50383160 (CHEMBL2031881) Show SMILES CNC(=O)c1ccc(c(F)c1)-c1ccc2C(=O)N(CCN3CCCC3)CCc2c1 Show InChI InChI=1S/C23H26FN3O2/c1-25-22(28)18-5-6-19(21(24)15-18)16-4-7-20-17(14-16)8-11-27(23(20)29)13-12-26-9-2-3-10-26/h4-7,14-15H,2-3,8-13H2,1H3,(H,25,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-(R)-alpha-methylhistamine from human H3 receptor expressed in HEK293T cells after 120 mins by scintillation counting				J Med Chem 55: 2452-68 (2012) Article DOI: 10.1021/jm300011d BindingDB Entry DOI: 10.7270/Q2736RZR
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50383160 (CHEMBL2031881) Show SMILES CNC(=O)c1ccc(c(F)c1)-c1ccc2C(=O)N(CCN3CCCC3)CCc2c1 Show InChI InChI=1S/C23H26FN3O2/c1-25-22(28)18-5-6-19(21(24)15-18)16-4-7-20-17(14-16)8-11-27(23(20)29)13-12-26-9-2-3-10-26/h4-7,14-15H,2-3,8-13H2,1H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human ERG by IonWorks assay				J Med Chem 55: 2452-68 (2012) Article DOI: 10.1021/jm300011d BindingDB Entry DOI: 10.7270/Q2736RZR
					More data for this Ligand-Target Pair