BDBM50383174 CHEMBL2031910

SMILES: COc1ccc2c(Oc3ccc(NC(=O)c4c([C@@H]5CCCN5)n(C)n(-c5ccccc5)c4=O)nc3)ccnc2c1

InChI Key: InChIKey=IBWQJAQFQVORMS-QHCPKHFHSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50383174   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50383174 (CHEMBL2031910) Show SMILES COc1ccc2c(Oc3ccc(NC(=O)c4c([C@@H]5CCCN5)n(C)n(-c5ccccc5)c4=O)nc3)ccnc2c1 |r| Show InChI InChI=1S/C30H28N6O4/c1-35-28(23-9-6-15-31-23)27(30(38)36(35)19-7-4-3-5-8-19)29(37)34-26-13-11-21(18-33-26)40-25-14-16-32-24-17-20(39-2)10-12-22(24)25/h3-5,7-8,10-14,16-18,23,31H,6,9,15H2,1-2H3,(H,33,34,37)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	948	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of IGF1R by HTRF assay				J Med Chem 55: 1868-97 (2012) Article DOI: 10.1021/jm201331s BindingDB Entry DOI: 10.7270/Q23B616C
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50383174 (CHEMBL2031910) Show SMILES COc1ccc2c(Oc3ccc(NC(=O)c4c([C@@H]5CCCN5)n(C)n(-c5ccccc5)c4=O)nc3)ccnc2c1 |r| Show InChI InChI=1S/C30H28N6O4/c1-35-28(23-9-6-15-31-23)27(30(38)36(35)19-7-4-3-5-8-19)29(37)34-26-13-11-21(18-33-26)40-25-14-16-32-24-17-20(39-2)10-12-22(24)25/h3-5,7-8,10-14,16-18,23,31H,6,9,15H2,1-2H3,(H,33,34,37)/t23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of c-Met by HTRF assay				J Med Chem 55: 1868-97 (2012) Article DOI: 10.1021/jm201331s BindingDB Entry DOI: 10.7270/Q23B616C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50383174 (CHEMBL2031910) Show SMILES COc1ccc2c(Oc3ccc(NC(=O)c4c([C@@H]5CCCN5)n(C)n(-c5ccccc5)c4=O)nc3)ccnc2c1 |r| Show InChI InChI=1S/C30H28N6O4/c1-35-28(23-9-6-15-31-23)27(30(38)36(35)19-7-4-3-5-8-19)29(37)34-26-13-11-21(18-33-26)40-25-14-16-32-24-17-20(39-2)10-12-22(24)25/h3-5,7-8,10-14,16-18,23,31H,6,9,15H2,1-2H3,(H,33,34,37)/t23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by HTRF assay				J Med Chem 55: 1868-97 (2012) Article DOI: 10.1021/jm201331s BindingDB Entry DOI: 10.7270/Q23B616C
					More data for this Ligand-Target Pair