null

SMILES: COc1cc2nccc(Oc3ccc(NC(=O)N4CCC(Cc5ccccc5)C4=O)cc3F)c2cc1OC

InChI Key: InChIKey=XNEDFTVHEMGHBT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50383213   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50383213 (CHEMBL2032037) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)N4CCC(Cc5ccccc5)C4=O)cc3F)c2cc1OC Show InChI InChI=1S/C29H26FN3O5/c1-36-26-16-21-23(17-27(26)37-2)31-12-10-24(21)38-25-9-8-20(15-22(25)30)32-29(35)33-13-11-19(28(33)34)14-18-6-4-3-5-7-18/h3-10,12,15-17,19H,11,13-14H2,1-2H3,(H,32,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	37.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant c-met-mediated gastrin phosphorylation by HTRF assay				J Med Chem 55: 1858-67 (2012) Article DOI: 10.1021/jm201330u BindingDB Entry DOI: 10.7270/Q2ZK5HQP
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50383213 (CHEMBL2032037) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)N4CCC(Cc5ccccc5)C4=O)cc3F)c2cc1OC Show InChI InChI=1S/C29H26FN3O5/c1-36-26-16-21-23(17-27(26)37-2)31-12-10-24(21)38-25-9-8-20(15-22(25)30)32-29(35)33-13-11-19(28(33)34)14-18-6-4-3-5-7-18/h3-10,12,15-17,19H,11,13-14H2,1-2H3,(H,32,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	592	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of HGF-mediated c-met autophosphorylation in serum-starved human PC3 cells after 1 hr by electrochemiluminescent immunoassay				J Med Chem 55: 1858-67 (2012) Article DOI: 10.1021/jm201330u BindingDB Entry DOI: 10.7270/Q2ZK5HQP
					More data for this Ligand-Target Pair