BDBM50383215 CHEMBL2032039

SMILES: COc1ccc2c(OCc3nnc4ccc(cn34)-c3cc(F)c(F)c(F)c3)ccnc2c1

InChI Key: InChIKey=JPBRRXXILOTTRH-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50383215   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50383215 (CHEMBL2032039) Show SMILES COc1ccc2c(OCc3nnc4ccc(cn34)-c3cc(F)c(F)c(F)c3)ccnc2c1 Show InChI InChI=1S/C23H15F3N4O2/c1-31-15-3-4-16-19(10-15)27-7-6-20(16)32-12-22-29-28-21-5-2-13(11-30(21)22)14-8-17(24)23(26)18(25)9-14/h2-11H,12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant c-met-mediated gastrin phosphorylation by HTRF assay				J Med Chem 55: 1858-67 (2012) Article DOI: 10.1021/jm201330u BindingDB Entry DOI: 10.7270/Q2ZK5HQP
					More data for this Ligand-Target Pair