BDBM50383265 CHEMBL2032368
SMILES: FC(F)(F)c1ccc(cc1)-c1nnc2ccc(NC3CCCCC3)nn12
InChI Key: InChIKey=PVKRXEQHNSCYHU-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM50383265 (CHEMBL2032368) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genzyme Corp. Curated by ChEMBL | Assay Description Inhibition of human Pim-1 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate preincubated for 15 mins prior substrate addition measured after 45 mins by fluo... | J Med Chem 55: 2641-8 (2012) Article DOI: 10.1021/jm2014698 BindingDB Entry DOI: 10.7270/Q2Q2418B | |||||||||||
More data for this Ligand-Target Pair |