BDBM50383370 CHEMBL2030543

SMILES: CN(C)c1ccc(\C=C(/C#N)c2ccccc2Cl)cc1

InChI Key: InChIKey=XOQICXJZZWXQDG-SDNWHVSQSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50383370   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Mus musculus)	BDBM50383370 (CHEMBL2030543) Show SMILES CN(C)c1ccc(\C=C(/C#N)c2ccccc2Cl)cc1 Show InChI InChI=1S/C17H15ClN2/c1-20(2)15-9-7-13(8-10-15)11-14(12-19)16-5-3-4-6-17(16)18/h3-11H,1-2H3/b14-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Philipps University Curated by ChEMBL					Assay Description Inverse agonist activity at PPARbeta/delta in mouse C2C12 cells assessed as inhibition of Angptl4 expression after 24 hrs by RT-qPCR analysis				J Med Chem 55: 2858-68 (2012) Article DOI: 10.1021/jm2017122 BindingDB Entry DOI: 10.7270/Q2XK8GK9
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Mus musculus)	BDBM50383370 (CHEMBL2030543) Show SMILES CN(C)c1ccc(\C=C(/C#N)c2ccccc2Cl)cc1 Show InChI InChI=1S/C17H15ClN2/c1-20(2)15-9-7-13(8-10-15)11-14(12-19)16-5-3-4-6-17(16)18/h3-11H,1-2H3/b14-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Philipps University Curated by ChEMBL					Assay Description Displacement of fluormone Pan-PPAR Green from mouse recombinant GST-tagged PPARbeta/delta LBD after 60 mins by TR-FRET assay				J Med Chem 55: 2858-68 (2012) Article DOI: 10.1021/jm2017122 BindingDB Entry DOI: 10.7270/Q2XK8GK9
					More data for this Ligand-Target Pair