null
SMILES: COc1c(Cl)cc(cc1Cl)C1C(C=NC=C1C(=O)OC\C=C\c1ccccc1)C(O)=O
InChI Key: InChIKey=FZRIAZSTBUMZCM-VMPITWQZSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human)) | BDBM50383765 (CHEMBL2030603) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 720 | n/a | n/a | n/a | n/a | n/a | n/a |
Ajinomoto Pharmaceuticals Co. Ltd Curated by ChEMBL | Assay Description Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca... | Bioorg Med Chem Lett 22: 3639-42 (2012) Article DOI: 10.1016/j.bmcl.2012.04.051 BindingDB Entry DOI: 10.7270/Q2QV3NJX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human)) | BDBM50383765 (CHEMBL2030603) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 840 | n/a | n/a | n/a | n/a | n/a | n/a |
Ajinomoto Pharmaceuticals Co. Ltd Curated by ChEMBL | Assay Description Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca... | Bioorg Med Chem Lett 22: 3639-42 (2012) Article DOI: 10.1016/j.bmcl.2012.04.051 BindingDB Entry DOI: 10.7270/Q2QV3NJX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human)) | BDBM50383765 (CHEMBL2030603) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 580 | n/a | n/a | n/a | n/a | n/a | n/a |
Ajinomoto Pharmaceuticals Co. Ltd Curated by ChEMBL | Assay Description Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca... | Bioorg Med Chem Lett 22: 3639-42 (2012) Article DOI: 10.1016/j.bmcl.2012.04.051 BindingDB Entry DOI: 10.7270/Q2QV3NJX | |||||||||||
More data for this Ligand-Target Pair |