BDBM50384016 CHEMBL2032288

SMILES: Nc1ncc(cc1-c1nc2ccc(NS(=O)(=O)c3ccc(F)cc3)cc2o1)-c1cnn(c1)C1CCNCC1

InChI Key: InChIKey=KYSXILVPHTYTKQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50384016   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50384016 (CHEMBL2032288) Show SMILES Nc1ncc(cc1-c1nc2ccc(NS(=O)(=O)c3ccc(F)cc3)cc2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C26H24FN7O3S/c27-18-1-4-21(5-2-18)38(35,36)33-19-3-6-23-24(12-19)37-26(32-23)22-11-16(13-30-25(22)28)17-14-31-34(15-17)20-7-9-29-10-8-20/h1-6,11-15,20,29,33H,7-10H2,(H2,28,30)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis				Bioorg Med Chem Lett 22: 4044-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4
					More data for this Ligand-Target Pair