BDBM50384032 CHEMBL2032161

SMILES: Nc1ncc(cc1-c1nc2ccc(Nc3ncccn3)cc2o1)-c1cnn(c1)C1CCNCC1

InChI Key: InChIKey=RCUBODWMLROCCW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50384032   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50384032 (CHEMBL2032161) Show SMILES Nc1ncc(cc1-c1nc2ccc(Nc3ncccn3)cc2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C24H23N9O/c25-22-19(10-15(12-29-22)16-13-30-33(14-16)18-4-8-26-9-5-18)23-32-20-3-2-17(11-21(20)34-23)31-24-27-6-1-7-28-24/h1-3,6-7,10-14,18,26H,4-5,8-9H2,(H2,25,29)(H,27,28,31)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis				Bioorg Med Chem Lett 22: 4044-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4
					More data for this Ligand-Target Pair