Found 3 hits for monomerid = 50384174 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50384174
(CHEMBL2029902)Show SMILES CN1CCN(CC1)C(=O)c1cc(Nc2ncc3ccn(C4CCCC4)c3n2)cn1C Show InChI InChI=1S/C22H29N7O/c1-26-9-11-28(12-10-26)21(30)19-13-17(15-27(19)2)24-22-23-14-16-7-8-29(20(16)25-22)18-5-3-4-6-18/h7-8,13-15,18H,3-6,9-12H2,1-2H3,(H,23,24,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Biogen Idec Inc.
Curated by ChEMBL
| Assay Description Inhibition of aurora B kinase |
Bioorg Med Chem Lett 22: 4033-7 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.085 BindingDB Entry DOI: 10.7270/Q24X58VK |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50384174
(CHEMBL2029902)Show SMILES CN1CCN(CC1)C(=O)c1cc(Nc2ncc3ccn(C4CCCC4)c3n2)cn1C Show InChI InChI=1S/C22H29N7O/c1-26-9-11-28(12-10-26)21(30)19-13-17(15-27(19)2)24-22-23-14-16-7-8-29(20(16)25-22)18-5-3-4-6-18/h7-8,13-15,18H,3-6,9-12H2,1-2H3,(H,23,24,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Biogen Idec Inc.
Curated by ChEMBL
| Assay Description Inhibition of aurora A kinase |
Bioorg Med Chem Lett 22: 4033-7 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.085 BindingDB Entry DOI: 10.7270/Q24X58VK |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 1
(Homo sapiens (Human)) | BDBM50384174
(CHEMBL2029902)Show SMILES CN1CCN(CC1)C(=O)c1cc(Nc2ncc3ccn(C4CCCC4)c3n2)cn1C Show InChI InChI=1S/C22H29N7O/c1-26-9-11-28(12-10-26)21(30)19-13-17(15-27(19)2)24-22-23-14-16-7-8-29(20(16)25-22)18-5-3-4-6-18/h7-8,13-15,18H,3-6,9-12H2,1-2H3,(H,23,24,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Biogen Idec Inc.
Curated by ChEMBL
| Assay Description Inhibition of CDK1 |
Bioorg Med Chem Lett 22: 4033-7 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.085 BindingDB Entry DOI: 10.7270/Q24X58VK |
More data for this Ligand-Target Pair | |