BDBM50384449 CHEMBL2035530
SMILES: COC(=O)CCSC\C=C(/C)CCn1cc(CCc2ccc(cc2)-c2ccccc2)nn1
InChI Key: InChIKey=LUXQNURJPSSXSC-RCCKNPSSSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Isoprenylcysteine carboxyl methyltransferase (Homo sapiens (Human)) | BDBM50384449 (CHEMBL2035530) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of ICMT in cell free system | ACS Med Chem Lett 3: 15-19 (2012) Article DOI: 10.1021/ml200106d BindingDB Entry DOI: 10.7270/Q26T0NPK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoprenylcysteine carboxyl methyltransferase (Homo sapiens (Human)) | BDBM50384449 (CHEMBL2035530) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai Curated by ChEMBL | Assay Description Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i... | Medchemcomm 7: 1016-1021 (2016) BindingDB Entry DOI: 10.7270/Q2C82C8P | |||||||||||
More data for this Ligand-Target Pair |